Different cartridges have vastly different ballistic characteristics, effective ranges, and intended applications. A scope optimized for a flat-shooting 6.5 Creedmoor at 1000 yards differs significantly from one suited for a hard-hitting 45-70 at brush-gun distances. Understanding how your cartridge performs helps you select optics that maximize its potential.
This guide examines scope selection by caliber category, helping you match magnification, reticle design, and turret features to your cartridge’s capabilities.
Table of Contents
- Ballistic Principles for Scope Selection
- Long-Range Cartridges
- Medium-Range Hunting Cartridges
- Brush and Woods Cartridges
- Rimfire Cartridges
- Magnum Cartridges
- Specialty Calibers
Ballistic Principles for Scope Selection
Trajectory and Holdover
Flat-shooting cartridges like 6.5 Creedmoor and .224 Valkyrie maintain minimal drop to extended distances, allowing simpler reticle designs and less turret adjustment. High-arc cartridges like .45-70 and .300 Blackout subsonic require significant holdover compensation—either through reticle subtensions or frequent turret dialing.
Effective Range
Match your scope’s magnification range to your cartridge’s effective distance. A .22 LR rarely shoots past 150 yards meaningfully; a 6.5 Creedmoor reaches 1200+ yards in skilled hands. Over-magnifying for a cartridge’s capability wastes money and adds unnecessary weight.
Recoil Considerations
Heavy-recoiling magnums demand rugged scope construction and generous eye relief. Budget scopes that survive .22 LR recoil may fail quickly on .338 Lapua. Match scope durability rating to cartridge recoil level—manufacturers publish recoil-tested cartridge lists.
Long-Range Cartridges
6.5 Creedmoor
The modern long-range standard, 6.5 Creedmoor offers exceptional accuracy with manageable recoil. This cartridge deserves quality glass with 4-16x minimum magnification, preferably 5-25x for reaching its 1200+ yard potential. First focal plane reticles with holdover subtensions complement the cartridge’s ranging capability. Exposed turrets allow precise elevation dialing.
6.5 Grendel
The AR-15 compatible 6.5 Grendel extends intermediate rifle capability to 800+ yards. LPVOs work for medium range; dedicated precision shooting warrants 4-14x or similar magnification. Consider the AR platform’s weight constraints when selecting optics.
.224 Valkyrie
Designed for extreme long-range from AR-15 platforms, .224 Valkyrie shoots flat with minimal wind drift. High magnification (6-24x) reveals the cartridge’s precision potential. The cartridge’s mild recoil allows lighter scope construction than magnum cartridges.
.308 Winchester
The versatile .308 serves hunting, precision, and tactical applications. Scope selection depends on intended use—hunting rigs work with 3-9x, precision rifles warrant 5-25x. The cartridge’s moderate recoil allows mid-weight scopes without durability concerns.
Medium-Range Hunting Cartridges
.30-06 Springfield
America’s classic hunting cartridge performs well from 0-500 yards on medium to large game. Traditional 3-9x scopes match the cartridge’s hunting heritage. Modern hunters may prefer 4-12x or 3-15x for added versatility. Duplex or BDC reticles suit hunting applications well.
.270 Winchester
The flat-shooting .270 reaches further than many realize—capable of 600+ yards on game. Consider 4-12x or 4-16x to utilize the cartridge’s extended range. Light to medium scope weight suits the typically lightweight rifles chambered in .270.
.243 Winchester
Excellent for varmints and deer-sized game, .243 offers flat trajectory with light recoil. Youth and smaller-framed shooters often start here. The mild recoil allows virtually any scope construction. Match magnification to primary use—varmint hunting benefits from higher power than deer hunting.
Brush and Woods Cartridges
.45-70 Government
The classic lever-action cartridge delivers heavy bullets at moderate velocity—optimized for 200 yards and closer in heavy cover. Low magnification (1-4x or 2-7x) matches the cartridge’s effective range. Heavy recoil demands quality construction and generous eye relief (3.5+ inches). Scout scopes suit lever actions chambered in .45-70.
.30-30 Winchester
The deer hunter’s traditional choice, .30-30 works inside 200 yards in timber and brush. Low magnification serves the cartridge best—1-4x, 2-7x, or fixed 4x scopes excel. Light, compact scopes preserve lever-action handling characteristics.
.357 Magnum (Rifle)
Lever-action .357 rifles offer low recoil and economical shooting for deer-sized game inside 150 yards. Low power optics (1-4x to 3-9x) match effective range. The light recoil permits any scope construction. Consider red dots for brush gun applications.
Rimfire Cartridges
.22 LR
The world’s most popular cartridge, .22 LR rarely shoots meaningfully past 150 yards. Parallax becomes critical at typical rimfire distances—select scopes with 50-yard parallax or adjustable parallax. Magnification from 3-9x to 4-12x covers most applications. Budget scopes serve rimfire adequately; save premium investments for centerfire rifles.
.17 HMR
The flat-shooting .17 HMR extends rimfire capability to 200+ yards for varmints. Higher magnification (4-12x to 6-18x) reveals the cartridge’s accuracy potential. Fine crosshairs suit small targets at distance. Quality optics show the .17 HMR’s capabilities that budget glass obscures.
.22 WMR
Between .22 LR and .17 HMR in capability, .22 WMR serves varmint and small game hunters. Medium magnification (3-9x to 4-12x) matches the cartridge’s 150-yard practical range. Similar scope selection to .17 HMR but with slightly less magnification emphasis.
Magnum Cartridges
.300 Winchester Magnum
The benchmark long-range hunting magnum, .300 Win Mag reaches 1000+ yards on game. Quality scopes with 4-16x or 5-25x magnification utilize the cartridge’s range. Significant recoil demands rugged construction and 3.5-4+ inch eye relief. Expect to invest in proven magnum-rated scopes.
.338 Lapua Magnum
Extreme long-range capability demands premium optics. High magnification (7-35x) for ELR shooting, exceptional glass quality for spotting at distance, and battle-proven durability for the punishing recoil. Budget $1500-3000+ for optics matching this cartridge’s capability.
.300 Weatherby Magnum
Blazing velocity extends hunting range significantly. Similar scope requirements to .300 Win Mag but with even more emphasis on eye relief due to sharper recoil. Quality 4-16x to 6-24x scopes serve the cartridge well.
Specialty Calibers
.50 Beowulf
The big-bore AR cartridge delivers massive energy inside 200 yards. Low magnification (1-6x to 1-8x LPVOs) matches effective range. Heavy recoil requires attention to eye relief and mount security. Red dots work well for close-range applications.
.450 Bushmaster
Straight-wall hunting cartridge for restricted states, .450 Bushmaster works inside 250 yards. Low to medium magnification (2-7x to 3-9x) matches capability. Similar considerations to other big-bore, moderate-range cartridges.
6mm ARC
The newest long-range AR-15 cartridge, 6mm ARC shoots flat to 800+ yards. Modern LPVOs (1-8x to 1-10x) or precision scopes (4-16x) serve different applications. The cartridge’s mild recoil allows lighter scope construction.
Caliber-Specific Scope Guides
Explore our detailed guides for specific calibers:
- Best Scopes for 460 XVR
- Best 300 Win Mag Loads for 1000 Yards
- Best Scopes for 357 Lever Action
- Best Scopes for 6.5 Grendel AR
- Best 22LR Scope for Hunting
- Best Scope for 338 Win Mag
- Best Long Range Scope for 6.5 Grendel
- Best Long Range Scope for 224 Valkyrie
- Best Scopes for 50 Beowulf
- Best 56mm Scope for Long Range Shooting
- Best Long-Range Rifle Scope for 1000+ Yards
Conclusion: Let Your Cartridge Guide Selection
Your cartridge’s ballistic characteristics should drive scope selection. High-velocity, flat-shooting rounds justify precision optics with high magnification. Brush-gun cartridges need speed and low power. Magnums demand rugged construction. Rimfires need appropriate parallax settings.
Match your scope investment to your cartridge’s capability—premium glass reveals what precision cartridges can do, while budget optics adequately serve close-range applications. Understanding your cartridge’s strengths and limitations leads to smarter scope selection.

